Navira

Navira Quality Systems Gap Assessment & Remediation

A founder-led Phase 1 GMP gap assessment that identifies gaps in your quality systems and builds CSV/CSA-aligned remediation plans. GCP, GVP, and GDP gap assessments are deferred to Phase 3 (2028+).

During the design-partner phase, engagements are founder-led by Vimal Veereshwarayya, PhD, RAC, working with a CSV/CSA contractor.

Phase 1: GMP
21 CFR Part 11-aligned
ALCOA+ aligned
Annex 22 (Draft 2025)
Assessment Approach

Structured. Evidence-Based. Actionable.

Navira Quality Systems gap assessments follow a rigorous, founder-led methodology aligned to regulatory expectations — delivering findings structured for regulator review and CSV/CSA-aligned remediation plans that get closed. During 2026 H2 we run two active founding partners at a time.

Phase 1 GMP current-state assessment

Gap identification against 21 CFR Part 11-aligned controls, ALCOA+, and GAMP 5 as internal-control references

Annex 22 (Draft 2025) internal-control readiness review

CSV/CSA-aligned remediation planning

Progress tracking framework

Assessment Phases

Four-Phase Methodology

From scoping through to a delivered remediation roadmap — structured to minimise time on-site and maximise output quality.

01

Scope & Planning

Define assessment scope, regulatory baseline, and success criteria.

02

Current-State Assessment

Document existing systems, processes, configurations, and controls.

03

Gap Analysis

Compare current state against Phase 1 GMP internal-control references and 21 CFR Part 11-aligned controls.

04

Remediation Planning

Develop actionable remediation roadmap with prioritised.

Common Gap Categories

Where Gaps Are Found

Six categories account for the majority of gaps identified across Phase 1 GMP environments using advisory AI.

01

GMP Audit-Trail Gaps

Audit-trail completeness, record retention, access controls, and data-integrity (ALCOA+) coverage across your GMP records.

02

MIRA Human-in-the-Loop Gaps

How advisory AI output is reviewed and approved — confirming a human-in-the-loop control sits ahead of any GxP-critical decision.

03

Annex 22 (Draft 2025) Readiness

Internal-control readiness against the Annex 22 draft, treated as an internal-control reference for AI use in GMP.

04

CSV / CSA Coverage

Computer system validation and assurance coverage, intended-use definition, and known-limitations documentation.

05

Change Management

Change control procedures, impact assessment for model/prompt/retrieval updates, and notification obligations.

06

Training & Competency

GMP training programmes, role-based curricula, training record completeness, and competency verification.

Deliverables

What You Receive

Every Navira Quality Systems gap assessment closes with a structured, regulator-ready deliverable package.

Gap Assessment Report

Full documentation of identified gaps, severity ratings, risk classifications, and supporting evidence.

CSV/CSA-Aligned Remediation Roadmap

Prioritised action plan with owners, effort estimates, dependencies, and target completion timelines.

Progress Tracking Framework

Structured framework for monitoring gap closure progress and reporting compliance improvement over time.

Ready to See Verixa in Action?

A focused walkthrough of Phase 1 GMP Core. 30 minutes. No obligations.